How it strikes a historian.

'how It Actually Was'? a Historian Responds to 'on Historical Contextualisation'

I found Lorie Charlesworth's article welcome, perceptive, impressively researched and, insofar as it is a manifesto, worthy of support. Here, I am singling out a small (though significant) part to comment on, largely because I find so little to disagree with in the rest of it. Her argument seems familiar, with good reason. In many ways the socio-legal project's relationship with black-letter la...

'It takes a village' strikes a chord.

Platelet Refractoriness and how it is formed

Abstract Background and Objectives Transfusion of platelet has become one of the main treatments for thrombocytopenic patients to reduce the severity and frequency of bleeding consequences. Failure to attain the desired level of platelets in a patient following platelet transfusion is defined as platelet refractoriness. The purpose of present paper is to review and study the mechanisms involve...

Occupational Stress and How to Confront It: A Case Study of a Hospital in Shiraz

Background: Although all jobs can be stressful, occupational stress is an important issue in jobs that deal with human health. Evidence indicates that nursing is a stressful occupation. Objective: This research evaluated factors affecting occupational stress and strategies for coping with it. Methods: This cross-sectional descriptiv...

How it acts, how it works

Interferon beta (IFNβ) and glatiramer acetate (GA) were the first immunomodulators approved to the treatment of relapsing-remitting multiple sclerosis (MS) and clinically isolated syndromes. Despite the enlargement of the therapeutic armamentarium, IFNβ and GA remain the most widely drugs and the therapeutic mainstay of MS. Objective: To review the mechanisms of action of IFNβ and GA and main c...